milk thistle to help to stop lung cancer

In addition, Tyagi and collaborators compared the effects of silibinin to drugs currently in clinical trials for lung cancer.

Compared to these multi-million dollar drugs, naturally occurring silibinin blocked not only the expression of COX2 and iNOS, but also the migration of existing lung cancer cells.

"What we showed is that STAT1 and STAT3 may be promising therapeutic targets in the treatment of lung cancer, no matter how you target them," Tyagi stated. ".... this text is below...

 

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"...Although milk thistle use has been documented for nearly 2,000 years, very little solid science exists to validate the beneficial effects on human health. Cells communicate with one another through a complex series of signals to achieve an end result, normally the creation of a protein or the completion of an enzymatic reaction. When this chain is broken as a result of poor diet or lifestyle choices that affect metabolic homeostasis, diseases such as cancer are allowed to develop and manifest in tissues throughout the body."  ...this text below...
"...Researchers found that when the chain is broken, tumor growth is halted and metastatic growth stops. They found that a derivative of milk thistle called silibinin was able to inhibit the upstream signals that lead to the expression of COX2 and iNOS and help prevent lung cancer."
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"...Over the course of 2000 years, milk thistle (Silybum marianum) has earned a beneficial reputation in matters relating to the liver, kidneys and gall bladder. Its most well known compound, the flavonoid silymarin derived from the seed of the plant, has both antioxidant and anti-inflammatory properties and has been the subject of many animal and human studies that have yielded mixed results. The most recent study of note focused on silibinin, another component of milk thistle, and its effect on cancer cells in mice.

In a
study published in the journal Molecular Carcinogenesis,researchers at the University of Colorado Cancer Center treated lung cancer cells in mice with silibinin and found the compound inhibited tumorigenesis in part by targeting the tumor’s microenvironment. "   see this below...
 

 

  

Milk thistle extract shown to halt lung cancer progression in its tracks

Wednesday, December 07, 2011 by: John Phillip
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(NaturalNews) Lung cancer is a devastating disease with a traditionally poor survival rate of less than ten percent after five years from diagnosis. There are a number of well documented triggers that cause tissue damage that eventually results in DNA damage, allowing lung cancer cells to develop and spread. Researchers from the University of Colorado publishing in the journal Molecular Carcinogenesis found that treatment with silibinin, a major component of milk thistle, effectively treated wound development in lung cancer cells by halting the disease and preventing metastasis. Long known for its rejuvenating effects on the liver, milk thistle is now emerging as a viable therapy to help prevent and reverse the damage caused by years of cellular breakdown in lung tissue.

Although milk thistle use has been documented for nearly 2,000 years, very little solid science exists to validate the beneficial effects on human health. Cells communicate with one another through a complex series of signals to achieve an end result, normally the creation of a protein or the completion of an enzymatic reaction. When this chain is broken as a result of poor diet or lifestyle choices that affect metabolic homeostasis, diseases such as cancer are allowed to develop and manifest in tissues throughout the body.

 

Milk Thistle Halts the Inflammatory Chain Known to Promote Lung Cancer Progression

Big Pharma frequently looks to break these chain reactions in an unnatural way; it halts metabolic processes in the body commonly with undesired or potentially deadly consequences. COX2 and iNOS are two enzymes that are involved in a chain of actions that elicit an inflammatory response to wounds and infectious processes. If you were to cut yourself, inflammation at the local site is a desired response that will aid healing. Unfortunately, systemic inflammation caused by excess body weight and poor dietary choices is a serious problem underlying many chronic diseases including lung cancer.

Both COX2 and iNOS aid tumor growth when they remain in circulation as a response to chronic inflammation. Two transcription factors known as STAT1 and STAT3 allow the blueprint of DNA to bind with proteins that continue the signal cascade, eventually leading to the production of harmful COX2 and iNOS. Researchers found that when the chain is broken, tumor growth is halted and metastatic growth stops. They found that a derivative of milk thistle called silibinin was able to inhibit the upstream signals that lead to the expression of COX2 and iNOS and help prevent lung cancer.

 


Lead study authors concluded: "What we showed is that STAT1 and STAT3 may be promising therapeutic targets in the treatment of lung cancer... and that naturally-derived products like silibinin may be as effective as today's best treatments." Milk thistle represents another natural compound that provides a powerful effect to prevent and treat chronic diseases. Alternative health experts recommend supplementing with 250 mg of a standardized milk thistle extract each day to fight the threat of lung cancer.
 


Sources for this article include:
http://onlinelibrary.wiley.com/doi/10.1002/mc.20851/abstract;jsession...
http://www.sciencedaily.com/releases/2011/11/111115145236.htm
http://www.eurekalert.org/pub_releases/2011-11/uocd-mte111511.php
http://www.nutritionhorizon.com/news/Milk-Thistle-Stops-Lung-Cancer-i...

About the author:
John Phillip is a Health Researcher and Author who writes regularly on the cutting edge use of diet, lifestyle modifications and targeted supplementation to enhance and improve the quality and length of life. John is the author of 'Your Healthy Weight Loss Plan', a comprehensive EBook explaining how to use Diet, Exercise, Mind and Targeted Supplementation to achieve your weight loss goal. Visit My Optimal Health Resource to continue reading the latest health news updates, and to download your Free 48 page copy of 'Your Healthy Weight Loss Plan'.



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"...findings are encouraging in that some day they may lead to more effective treatments for alcohol and food addictions. Meanwhile, the link between the two compulsive disorders may suggest that the same kind of programs, which have helped alcoholics achieve sobriety, may also allow overeaters to tap into their own higher power to surmount their problems. Both Alcoholics Anonymous and Overeaters Anonymous take a spiritual approach and rely on group support. For those who want the latter without the former, Weight Watchers uses the group dynamic..."

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Milk thistle halts spread of lung cancer

ANI Nov 16, 2011, 03.31PM IST
 

 

 

 

 

An Indian origin scientist has suggested that silibinin, a major component of milk thistle, may be a promising therapeutic compound in the treatment of lung cancer.

Alpna Tyagi, PhD, of the University of Colorado Skaggs School of Pharmacy, and her team found that treatment with silibinin stopped the spread of these lung cancers in mouse.

 

"And also that naturally-derived products like silibinin may be as effective as today's best treatments," she added.

The study has been recently published in the journal Molecular Carcinogenesis. ...

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